Intuitive Staging Correlates With King's Clinical Stage.

Intuitive Staging Correlates With King's Clinical Stage.
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DOI:
10.1080/21678421.2020.1867181
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发表时间:
2021-08
影响因子:
2.8
通讯作者:
Al-Chalabi A
Al-Chalabi A
中科院分区:
医学4区
文献类型:
--
作者:
Al Khleifat A;Balendra R;Fang T;Al-Chalabi A

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肌萎缩性侧索硬化症(ALS)的临床分期可以使用King分期和一个简单的方案来划分,该方案基于中枢神经系统受累区域的数量和是否存在显著的营养或呼吸衰竭。重要的是,指定的临床阶段符合预期,并且通常与卫生保健专业人员如何直观地对患者进行分期相对应。因此,我们调查了King 's临床渐冻症分期与卫生保健专业人员直观分配的渐冻症分期之间的关系。我们写了17个病例,描述了不同疾病阶段的ALS患者,从非常早期的有限疾病到严重的多领域疾病。在两次研讨会中,我们要求医疗保健专业人员直观地呈现小片段,并将答案与实际的金氏ALS临床阶段进行比较。King 's临床ALS分期与直观分配的分期有很好的相关性,Spearman 's Rank相关系数为0.64 (p<0.001)。不同类型或不同经验水平的实践者所分配的直觉阶段没有差异。在一系列ALS情况中,King的临床ALS阶段与一系列医疗保健专业人员分配的直观ALS阶段相对应。
Clinical stage in amyotrophic lateral sclerosis (ALS) can be assigned using King’s staging with a simple protocol based on the number of CNS regions involved and the presence of significant nutritional or respiratory failure. It is important that the assigned clinical stage matches expectations, and generally corresponds with how a health care professional would intuitively stage the patient. We therefore investigated the relationship between King’s clinical ALS stage and ALS stage as intuitively assigned by health care professionals. We wrote 17 case vignettes describing people with ALS at different disease stages from very early limited disease involvement through to severe, multi-domain disease. During two workshops, we asked health care professionals to intuitively stage the vignettes and compared the answers with the actual King’s clinical ALS stage. There was a good correlation between King’s clinical ALS stage and intuitively assigned stage, with a Spearman’s Rank correlation coefficient of 0.64 (p<0.001). There was no difference in the intuitive stages assigned by practitioners of different types or at different levels of experience. Across a spectrum of ALS scenarios, King’s clinical ALS stage corresponds to intuitive ALS stage as assigned by a range of health care professionals.
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