INFLUENCE OF RELATIVE HUMIDITY ON AEROSOL STABILITY OF DIFFERENT STRAINS OF FOOT-AND-MOUTH DISEASE VIRUS SUSPENDED IN SALIVA
INFLUENCE OF RELATIVE HUMIDITY ON AEROSOL STABILITY OF DIFFERENT STRAINS OF FOOT-AND-MOUTH DISEASE VIRUS SUSPENDED IN SALIVA
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DOI：
10.1099/0022-1317-15-1-25
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发表时间：
1972-01-01
影响因子：
3.8
通讯作者：
DONALDSON, AI
中科院分区：
文献类型：
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作者：
DONALDSON, AI
比较了8株口蹄疫病毒悬浮于牛唾液中的气溶胶稳定性。使用的菌株为O 1bfs 1860、O 1 pacheco、O 1 lombardy、O2 brescia、A5 eystrup（tübingen）、A22 iraq 24/64、Cnoville和Clebanon 3/69。将菌株作为气溶胶云1秒进行比较。在不同相对湿度下老化，并在70%和55%相对湿度（RH）下储存长达60分钟。在气溶胶云中1秒。所有病毒株在60%RH及以上时显示最大感染性存活。低于60% RH时，感染性降低，低于20% RH时几乎未检测到感染性。在低RH的气溶胶存活的A株是约10倍高于O和C株。在70%或55%RH下储存气溶胶期间，菌株的稳定性显著不同。衰变率为1.1 log./ hr（O 1 pacheco）至3.2 log./ hr（O 1bfs 1860），在70% RH和2.1 log./ hr（O 1 pacheco）至3.3 log./ hr（A22伊拉克），55% RH。在55%RH下，某些菌株的感染性回收率太低，无法确定衰减率。
Comparisons were made of the aerosol stabilities of eight strains of foot-and-mouth disease (FMD) virus suspended in bovine salivary fluid. The strains used were O1bfs1860, O1pacheco, O1lombardy, O2brescia, A5eystrup(tübingen), A22iraq24/64, Cnovilleand Clebanon3/69. The strains were compared as aerosol clouds 1 sec. old at different relative humidities and during storage for up to 60 min. at 70% and 55% relative humidity (RH). In aerosol clouds 1 sec. old all virus strains showed maximum survival of infectivity at 60% RH and above. Below 60% RH, infectivity was reduced and little infectivity was detected below 20% RH. At low RH the aerosol survival of the A strains was about 10-fold higher than that for the O and C strains. The strains differed significantly in stability during storage of aerosols at 70% or 55% RH. Decay rates ranged from 1.1 log./hr (O1pacheco) to 3.2 log./hr (O1bfs1860) at 70% RH and from 2.1 log./hr (O1pacheco) to 3.3 log./hr (A22iraq) at 55% RH. At 55% RH the infectivity recoveries of some strains were too low for decay rates to be determined.