Effect of specific antisera upon Streptococcus mutans adherence to saliva-coated hydroxylapatite
Effect of specific antisera upon Streptococcus mutans adherence to saliva-coated hydroxylapatite
复制标题
特异性抗血清对变形链球菌粘附唾液涂层羟基磷灰石的影响
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
R. Russell
中科院分区：
文献类型：
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作者：
C. Douglas;R. Russell
IgG fractions of antisera against Streptococcus mutans cell-surface protein antigens A and B were used to examine the role of these molecules in adherence to saliva-coated hydroxylapatite. Anti-B antibody inhibited S. mutans adherence by 20–50% depending upon the strain used, while anti-A antibody was without effect. Some IgG-mediated agglutination of cells occurred in the course of these experiments which was overcome by using Fab fragments prepared from the anti-A and anti-B IgG's. Anti-B Fab inhibited S. mutans adherence by 50% but anti-A Fab had no effect. These observations suggest that antigen B is an important factor in the adherence of S. mutans to saliva-coated hydroxylapatite.
