Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants.
Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants.
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DOI：
10.1039/c2cc34404a
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发表时间：
2012-08
影响因子：
4.9
通讯作者：
Jian Zhang;Hefang Shi;Yuyong Ma;Biao Yu
中科院分区：
文献类型：
--
作者：
Jian Zhang;Hefang Shi;Yuyong Ma;Biao Yu
以地高辛为原料，经糖苷配基制备Hoodigogenin A，并以邻炔基苯甲酸酯为供体组装脱氧三糖，快速合成了Hoodia的食欲抑制成分孕烷糖苷P57。
Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.