A rat model for evaluating physiological responses to femoral shaft fracture reduction using a surgical robot
A rat model for evaluating physiological responses to femoral shaft fracture reduction using a surgical robot
复制标题
使用手术机器人评估股骨干骨折复位生理反应的大鼠模型
DOI：
--
复制
发表时间：
2008
影响因子：
2.8
通讯作者：
T. Gosling
中科院分区：
文献类型：
--
作者：
M. Oszwald;R. Westphal;P. O'loughlin;D. Kendoff;T. Hufner;F. Wahl;C. Krettek;T. Gosling
治疗移位的股骨干骨折的第一步是充分复位骨折碎片。手动复位可能具有挑战性，并且经常与软组织损伤相关，特别是在反复尝试复位时。长期和反复复位操作引起的局部和全身炎症反应的程度尚未完全确定。我们设计了一种手术技术，利用机器人复位装置用于大鼠。通过截骨术模拟股骨骨折。该机器人能够再现手动和引导的精度降低，在一个单一的路径运动。外固定器是专门设计来操纵大鼠股骨，也用于固定截骨区域。首先，在8个股骨中评估复位准确性，然后在22个股骨中分析固定器放置质量和复位准确性。在第一个病例中，100%的股骨被准确复位。在第二个病例中，91%的标本成功稳定固定，86%的标本实现了准确复位。我们证明了机器人辅助骨折复位模型的可行性，该模型可用于通过生物化学和组织病理学方法分析复位对周围软组织的影响。未来的一个方面将是评估机器人是否赋予骨折复位与传统技术相比的优势，这将对骨科手术中使用机器人设备产生重大影响。© 2008骨科研究学会。出版社：Wiley Periodicals，Inc. J Orthop Res
The first step in treatment of displaced femoral shaft fractures is adequate reduction of the fracture fragments. Manually performed, reduction can be challenging, and is frequently associated with soft tissue damage, especially when repeated reduction attempts are made. The magnitude of local and systemic inflammatory responses caused by prolonged and repeated reduction maneuvers has not been fully established. We devised an operative technique utilizing a robotic reduction device for use in a rat. A femoral fracture was simulated by means of an osteotomy. The robot enabled reproduction of both manual and guided precision reductions, performed in a single path movement. An external fixator was designed specifically to manipulate the rat femur and also for fixation of the osteotomy region. First, reduction accuracy was assessed in eight femurs, then the quality of fixator placement and reduction accuracy was analyzed in 22 femurs. In the first case, 100% of the femurs were accurately reduced. In the second case, 91% had successful stable fixation and an accurate reduction was achieved in 86% of the specimens. We demonstrated the feasibility of a model of robot‐assisted fracture reduction that could be used to analyze the effects of reduction on the surrounding soft tissue via biochemical and histopathological means. A future aspect will be to evaluate whether the robot confers an advantage in fracture reduction versus the conventional technique, which would have significant implications for the use of robotic devices in orthopaedic surgery. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res
影响因子：
2.2
作者：
Wang, WY;Smail, N;Chaudry, IH
通讯作者：
Chaudry, IH
在离体、灌注的大鼠后肢中，钝性损伤会增强白细胞介素 6，但不会增强肿瘤坏死因子。
DOI：
10.1097/00005373-199407000-00016
发表时间：
1994
期刊：
The Journal of trauma
影响因子：
--
作者：
Cipolle,MD;Pasquale,MD;Shearer,J;Caldwell,M;Cerra,F
通讯作者：
Cerra,F
DOI：
10.1152/ajpregu.00793.2005
发表时间：
2006-10-01
影响因子：
2.8
作者：
Levy, Ryan M.;Prince, Jose M.;Billiar, Timothy R.
通讯作者：
Billiar, Timothy R.