A negative emotional and economic judgment bias in major depression
A negative emotional and economic judgment bias in major depression
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DOI：
10.1007/s00406-013-0392-5
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发表时间：
2013-12-01
影响因子：
4.7
通讯作者：
Hurlemann, Ren
中科院分区：
文献类型：
--
作者：
Scheele, Dirk;Mihov, Yoan;Hurlemann, Ren
虽然重度抑郁症预计将成为2030年残疾调整生命年损失的三大原因之一，但人们对抑郁情绪状态在多大程度上会使社会经济决策偏离最佳结果知之甚少。一个研究负面情绪和社会经济决策之间相互作用的实验框架是最后通牒游戏（UG），其中公平，合作的玩家利他地惩罚不公平，不合作的玩家。为了评估利他惩罚对抑郁情绪的潜在易感性，我们对20名诊断为复发性重度抑郁症的抑郁症患者和20名健康对照者进行了重复的UG任务。此外，情绪负荷图片的效价和唤醒评级，以评估情绪判断的抑郁情绪相关的扭曲从所有参与者。与健康对照组相比，抑郁症患者在UG中过度认可不公平的建议，并对情绪刺激进行了负面判断。因此，重度抑郁症与负面情绪偏见有关，这种偏见阻碍了社会经济决策，并产生了巨大的个人成本。
Although major depression is projected to be among the top three causes of disability-adjusted life years lost in 2030, relatively little is known concerning the extent to which depressed mood states can bias social-economic decision making away from optimal outcomes. One experimental framework to study the interaction between negative emotion and social-economic decisions is the ultimatum game (UG), where the fair, cooperative player altruistically punishes the unfair, non-cooperative player. To assess a potential susceptibility of altruistic punishment to depressed mood, we repeatedly administered the UG task to a cohort of 20 currently depressed patients with a diagnosis of recurrent major depressive disorder and 20 healthy controls. Furthermore, valence and arousal ratings of emotionally laden pictures were obtained from all participants in order to assess a depressed mood-related distortion of emotion judgments. Compared to healthy controls, depressed patients over-sanctioned unfair proposals in the UG and judged emotional stimuli too negatively. Thus, major depression is associated with a negative emotional bias that hampers social-economic decision making and produces large personal costs.