Weight changes in the terminal stages of chronic obstructive pulmonary disease. Relation to respiratory function and prognosis.
Weight changes in the terminal stages of chronic obstructive pulmonary disease. Relation to respiratory function and prognosis.
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慢性阻塞性肺疾病末期的体重变化。
DOI：
10.1164/arrd.1967.95.4.556
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发表时间：
1967
期刊：
影响因子：
--
通讯作者：
A. Gyselen
中科院分区：
文献类型：
--
作者：
É. Vandenbergh;K. P. Van de Woestijne;A. Gyselen
在呼吸功能不全的终末期出现明显的体重减轻是一种常见的临床表现(1-3)。这可能导致恶病质，结果是怀疑是恶性的(3-5)。然而，关于体重下降的开始、程度、持续时间、原因以及对肺功能的影响，文献中的数据有限。在220名肺气肿患者中，温克(5)提到了19名因体重显著下降或恶病质而住院的患者。在199名患者中，他发现130名患者的实际体重至少比他们的理论体重轻10%，这是由Broca指数确定的。Mitchell和Filley(2)观察到他们的150名慢性阻塞性疾病患者中有51%的人体重减轻；在14%的人中，这种体重减轻超过呼吸困难前期体重的20%。
The occurrence of marked weight loss during the terminal stages of respiratory insufficiency is a frequent clinical finding (1-3). This can lead to cachexia, with the result that suspicion of malignancy arises (3-5). Nevertheless, only limited data are available in the literature on the beginning, the degree, the duration, the causes, and the repercussions on lung function due to this weight loss.In a group of 220 emphysematous patients Wenk (5) mentioned 19 patients admitted to hospital because of marked weight loss or cachexia. Among 199 of these patients he found 130 whose actual weight was at least 10 per cent less than their theoretic body weight, as determined by the index of Broca. Mitchell and Filley (2) observed weight loss in 51 per cent of their group of 150 patients with chronic obstructive disease; in 14 per cent, this weight loss exceeded the predyspnea body weight by 20 per cent.