The importance of nitrogen substituents in chiral amino thiol ligands for the asymmetric addition of diethylzinc to aromatic aldehydes
The importance of nitrogen substituents in chiral amino thiol ligands for the asymmetric addition of diethylzinc to aromatic aldehydes
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DOI：
10.1039/a707937k
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发表时间：
1998-02-07
影响因子：
4.9
通讯作者：
Harding, M
中科院分区：
文献类型：
--
作者：
Anderson, JC;Harding, M
一系列由（S）-缬氨酸衍生的具有立体氮给体能力的N，S-螯合配体催化二乙基锌与芳香醛的加成反应，产物仲醇的ee值可达82%.
A new series of N,S-chelate ligands derived from (S)-valine, which possess the capability of a stereogenic nitrogen donor atom, are catalysts for the addition of diethylzinc to aromatic aldehydes and gave the product secondary alcohols in up to 82% ee.