Phylogeography of swine influenza H3N2 in the United States: translational public health for zoonotic disease surveillance.
Phylogeography of swine influenza H3N2 in the United States: translational public health for zoonotic disease surveillance.
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美国猪流感 H3N2 的系统发育地理学：人畜共患疾病监测的转化公共卫生。
DOI：
10.1016/j.meegid.2012.09.015
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Mei,Changjiang
中科院分区：
文献类型：
--
作者：
Scotch,Matthew;Mei,Changjiang
系统发育地理学领域因其在分子进化和物种地理迁移方面的应用而受到广泛关注。最近的工作包括传染病，尤其是人畜共患 RNA 病毒，如流感和狂犬病。病毒的系统发育地理学有可能促进公共卫生部门、农业部门和野生动物机构等机构的监测。然而，人们对这些机构如何利用系统发育地理学进行应用监测以及动物和人类序列数据的整合知之甚少。在这里，我们强调它支持“转化公共卫生”的潜力，可以将序列数据带到监测的最前沿。我们重点关注猪流感 H3N2，因为最近它与一种也感染人类的变异形式有关。我们讨论了应用监测的影响以及动物和公共卫生机构采用综合生物医学信息学方法的必要性。
The field of phylogeography has received a lot of attention for its application to molecular evolution and geographic migration of species. More recent work has included infectious diseases especially zoonotic RNA viruses like influenza and rabies. Phylogeography of viruses has the potential to advance surveillance at agencies such as public health departments, agriculture departments, and wildlife agencies. However, little is known about how these agencies could use phylogeography for applied surveillance and the integration of animal and human sequence data. Here, we highlight its potential to support ‘translational public health’ that could bring sequence data to the forefront of surveillance. We focus on swine influenza H3N2 because of the recent link to a variant form that has also infected humans. We discuss the implications to applied surveillance and the need for an integrated biomedical informatics approach for adoption at agencies of animal and public health.