Enhanced depth imaging spectral-domain optical coherence tomography
Enhanced depth imaging spectral-domain optical coherence tomography
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DOI：
10.1016/j.ajo.2008.05.032
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发表时间：
2008-10-01
影响因子：
4.2
通讯作者：
Pozonni, Maria C.
中科院分区：
文献类型：
--
作者：
Spaide, Richard F.;Koizumi, Hideki;Pozonni, Maria C.
目的：描述一种使用传统的光谱域(SD)光学相干断层扫描(OCT)获取脉络膜图像并使用这些图像评估脉络膜厚度测量的方法。设计：观察性病例系列。方法：通过将SD OCT设备放置到足够靠近眼睛的位置来获得图像，以获得没有瞳孔扩张的健康志愿者的眼底倒置图像。在以中心凹为中心的5-x 15度矩形内，获得了7个切片，每个切片包含100个平均扫描图像。每幅图像的中心凹下脉络膜厚度由独立的观察者测量。结果：每个受试者的脉络膜图像都可以评估脉络膜厚度。中心凹下平均脉络膜厚度右眼为318微米，左眼为335微米。双眼脉络膜厚度呈高度相关(r=0.82；P<0.01)。独立观察者的测量结果之间的相关性非常显著(右眼，r=0.93；左眼，r=0.97；P<；.001)。结论：这种方法提供了详细的、可测量的脉络膜图像，这是迄今为止在临床实践中难以成像的结构。
PURPOSE: To describe a method to obtain images of the choroid using conventional spectral-domain (SD) optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images.DESIGN: Observational case series.METHODS: The images were obtained by positioning the SD OCT device close enough to the eye to obtain an inverted representation of the fundus in healthy volunteers who did not have pupillary dilation. Seven sections, each comprised of 100 averaged scans, were obtained within a 5- x 15-degree rectangle centered on the fovea. The choroidal thickness under the fovea in each image was measured by independent observers.RESULTS: The choroidal thickness could be evaluated in every subject's choroidal image. The mean choroidal thickness under the fovea was 318 mu m in the right eye and 335 mu m in the left eye. The choroidal thickness showed a high correlation in both eyes (r = 0.82; P < .001). The correlation between the measurements performed by the independent observers was highly significant (right eye, r = 0.93; left eye, r = 0.97; P < .001 for both).CONCLUSIONS: This method provides detailed, measurable images from the choroid, a structure that heretofore has been difficult to image in clinical practice.