Thickening of the Left Atrial Wall Shortly After Radiofrequency Ablation Predicts Early Recurrence of Atrial Fibrillation
Thickening of the Left Atrial Wall Shortly After Radiofrequency Ablation Predicts Early Recurrence of Atrial Fibrillation
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DOI：
10.1253/circj.cj-10-0026
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发表时间：
2010-08-01
影响因子：
3.3
通讯作者：
Taniguchi, Koichi
中科院分区：
文献类型：
--
作者：
Yokokawa, Miki;Tada, Hiroshi;Taniguchi, Koichi
背景：房颤消融后的炎症反应可加重致心律失常活动，并导致房颤的早期复发。方法与结果：56例阵发性房颤患者行环肺静脉消融术(CPVA)前、术后1天和1个月的左房5个细分区域的心血管磁共振成像(CMRI)检查。在CPVA后平均7+/-10天，23名患者(41%)发生1次或1次以上房颤(ERAF组)，而33名患者(59%)在随访的第一个月内仍未发生房颤(非ERAF组)。CPVA术后第1天，两组患者左房壁厚度均增加，表现为高T2加权信号。但ERAF组LA顶板厚度及其增厚幅度大于非ERAF组(P
Background: Inflammatory responses following atrial fibrillation (AF) ablation may aggravate arrhythmogenic activity and cause an early recurrence of AF (ERAF).Methods and Results: In 56 patients who underwent circumferential pulmonary vein ablation (CPVA) for paroxysmal AF, cardiovascular magnetic resonance imaging (CMRI) was evaluated in 5 subdivided left atrial (LA) regions before the CPVA and at 1 day and 1 month after. At a mean of 7 +/- 10 days after the CPVA, 23 patients (41%) developed 1 or more episodes of AF (ERAF group), while 33 patients (59%) remained free from AF during the first month of follow up (no-ERAF group). LA wall thickness increased 1 day after the CPVA in both groups, as demonstrated by high T2-weighted signal. The LA roof thickness and its increase, however, were greater in the ERAF group than in the no-ERAF group (P