Long-term results of Gamma Knife surgery for arteriovenous malformations: 10- to 15-year follow up in patients treated with lower doses

Long-term results of Gamma Knife surgery for arteriovenous malformations: 10- to 15-year follow up in patients treated with lower doses
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DOI:
10.3171/sup.2006.105.7.64
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发表时间:
2006-12-01
影响因子:
4.1
通讯作者:
Inoue, Hiroshi K.
Inoue, Hiroshi K.
中科院分区:
医学1区
文献类型:
--
作者:
Inoue, Hiroshi K.

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对象。一些不良反应,如脑水肿、坏死、动脉狭窄、闭塞后出血和延迟囊肿形成已被报道为伽玛刀手术(GKS)治疗动静脉畸形(AVMs)的早期和晚期并发症。这些不良反应似乎在低剂量治疗方案中与经典的25戈瑞的高边缘剂量相比有所减少,因为对周围组织的辐射损伤最小。本文介绍了低剂量GKS治疗avm的远期疗效。114例AVMs患者接受低剂量GKS (
Object. Several adverse effects such as brain edema, necrosis, arterial stenosis, hemorrhage after obliteration, and delayed cyst formation have been reported as early and late complications of Gamma Knife surgery (GKS) for arteriovenous malformations (AVMs). These adverse effects seem to be decreased in a lower-dose treatment regimen compared with the classic higher margin doses of 25 Gy because the radiation insult to the surrounding tissue is minimized. Long-term results of lower-dose GKS for AVMs are presented.Methods. One hundred fourteen patients with AVMs were treated with lower-dose GKS (