INTENSITY-MODULATED ARC THERAPY WITH DYNAMIC MULTILEAF COLLIMATION - AN ALTERNATIVE TO TOMOTHERAPY
INTENSITY-MODULATED ARC THERAPY WITH DYNAMIC MULTILEAF COLLIMATION - AN ALTERNATIVE TO TOMOTHERAPY
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DOI：
10.1088/0031-9155/40/9/004
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发表时间：
1995-09-01
影响因子：
3.5
通讯作者：
YU, CX
中科院分区：
文献类型：
--
作者：
YU, CX
改善局部肿瘤控制和治愈更多癌症患者的愿望，加上计算机技术和直线加速器设计的进步，刺激了三维适形放疗技术的发展。优化的治疗方案旨在向目标提供高剂量，同时将对周围组织的剂量降至最低，可以通过空间调制光束强度的多个场或多层治疗来传递。本文介绍了一种新的方法，即强度调节治疗（IMAT），用于提供优化的治疗方案，以提高治疗率。它利用连续的龙门运动作为传统的治疗。不像传统的治疗，场的形状，这是符合多叶准直器，在龙门架旋转变化。不同光束角度下任意二维光束强度分布由多个叠加弧线传递。一个能够提供IMAT的系统已经实施。算例说明了该方法的可行性。这种新技术相对于断层治疗和其他基于切片的给药方案的优点也进行了讨论。
The desire to improve local tumour control and cure more cancer patients, coupled with advances in computer technology and linear accelerator design, has spurred the developments of three-dimensional conformal radiotherapy techniques. Optimized treatment plans, aiming to deliver high dose to the target while minimizing dose to the surrounding tissues, can be delivered with multiple fields each with spatially modulated beam intensities or with multiple-slice treatments. This paper introduces a new method, intensity-modulated are therapy (IMAT), for delivering optimized treatment plans to improve the therapeutic ratio. It utilizes continuous gantry motion as in conventional are therapy. Unlike conventional are therapy, the field shape, which is conformed with the multileaf collimator, changes during gantry rotation. Arbitrary two-dimensional beam intensity distributions at different beam angles are delivered with multiple superimposing arcs. A system capable of delivering the IMAT has been implemented. An example is given that illustrates the feasibility of this new method. Advantages of this new technique over tomotherapy and other slice-based delivery schemes are also discussed.