Surface functionalization of zirconium dioxide nano-adsorbents with 3-aminopropyl triethoxysilane and promoted adsorption activity for bovine serum albumin
Surface functionalization of zirconium dioxide nano-adsorbents with 3-aminopropyl triethoxysilane and promoted adsorption activity for bovine serum albumin
复制标题
3-氨丙基三乙氧基硅烷对二氧化锆纳米吸附剂进行表面功能化并提高对牛血清白蛋白的吸附活性
DOI：
10.1016/j.matchemphys.2016.03.042
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发表时间：
2016-06-15
影响因子：
4.6
通讯作者：
Xu, Yan
中科院分区：
文献类型：
--
作者：
Liu, Gen;Wu, Chaochao;Xu, Yan
以3-氨丙基三乙氧基硅烷（APTES）为改性剂，对二氧化锆（ZrO 2）纳米吸附剂进行表面功能化。改变APTES的加入量以确定最佳的改性程度，并通过APTES对本体ZrO 2微粒进行改性以进行比较。采用TEM、XRD、FT-IR、XPS、TG-DSC等手段对所合成的ZrO 2颗粒进行了表征。结果表明，ANIS分子通过Zr-O-Si键被化学固定在纳米ZrO 2表面，纳米ZrO 2具有较大的比表面积。在对牛血清白蛋白（BSA）的吸附中，纳米ZrO 2表现出较强的吸附活性，其中APTES改性后的纳米ZrO 2对BSA的吸附性能最好。在相同的吸附条件下，APTES-ZrO 2 -2对BSA的平衡吸附量约为纳米ZrO 2的2.3倍，是颗粒状ZrO 2的3.0倍。APTES-ZrO 2纳米吸附剂吸附容量的增加可归因于APTES-ZrO 2/BSA界面上氨基和羧基之间的化学相互作用。pH依赖性实验表明，BSA吸附和解吸的最佳pH值分别为5.0和9.0，表明BSA的吸附和释放可以通过调节溶液pH来简单控制。(C)2016爱思唯尔B. V.保留所有权利。
Surface functionalization of zirconium dioxide (ZrO2) nano-adsorbents was carried out by using 3-aminopropyl triethoxysilane (APTES) as the modifier. The addition amount of APTES was varied to determine the optimum modification extent, and the bulk ZrO2 microparticles were also modified by APTES for comparison. Some means, such as TEM, XRD, FT-IR, XPS and TG-DSC were used to character these ZrO2 particles. The results showed that the ANIS molecules were chemically immobilized on the surface of ZrO2 nanoparticles via Zr-O-Si bonds, and the nano-ZrO2 samples showed larger special surface area. In the adsorption of bovine serum albumin (BSA), nano-ZrO2 samples exhibited enhanced adsorption activity, and APTES Modified nano-ZrO2 with proper APTES content presented the best adsorption property. Under the same adsorption conditions, the equilibrium adsorption capacity of BSA on APTES-ZrO2-2 was almost 2.3 times as that on pristine nano-ZrO2 and 3.0 times as on bulk ZrO2 microparticles. The increased adsorption capacity of APTES-ZrO2 nano-adsorbents can be attributed to the chemical interaction between amino and carboxyl groups at APTES-ZrO2/BSA interface. The pH dependent experiments showed that the optimum pH value for the adsorption and desorption was 5.0 and 9.0, respectively, which suggested that the adsorption and release of BSA could be controlled simply by adjusting the solution pH condition. (C) 2016 Elsevier B.V. All rights reserved.