From space to time: Spatial inhomogeneities lead to the emergence of spatiotemporal sequences in spiking neuronal networks
From space to time: Spatial inhomogeneities lead to the emergence of spatiotemporal sequences in spiking neuronal networks
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从空间到时间:空间不均匀性导致尖峰神经元网络中时空序列的出现
DOI:
10.1371/journal.pcbi.1007432
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发表时间:
2019
影响因子:
4.3
通讯作者:
Arvind Kumar
中科院分区:
文献类型:
--
作者:
Sebastian Spreizer;A. Aertsen;Arvind Kumar
Spatio-temporal sequences of neuronal activity are observed in many brain regions in a variety of tasks and are thought to form the basis of meaningful behavior. However, mechanisms by which a neuronal network can generate spatio-temporal activity sequences have remained obscure. Existing models are biologically untenable because they either require manual embedding of a feedforward network within a random network or supervised learning to train the connectivity of a network to generate sequences. Here, we propose a biologically plausible, generative rule to create spatio-temporal activity sequences in a network of spiking neurons with distance-dependent connectivity. We show that the emergence of spatio-temporal activity sequences requires: (1) individual neurons preferentially project a small fraction of their axons in a specific direction, and (2) the preferential projection direction of neighboring neurons is similar. Thus, an anisotropic but correlated connectivity of neuron groups suffices to generate spatio-temporal activity sequences in an otherwise random neuronal network model.
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影响因子:
4.2
作者:
Senk J;Korvasová K;Schuecker J;Hagen E;Tetzlaff T;Diesmann M;Helias M.
通讯作者:
Helias M.
DOI:
10.1126/science.aat4422
发表时间:
2018-06-29
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Patriarchi T;Cho JR;Merten K;Howe MW;Marley A;Xiong WH;Folk RW;Broussard GJ;Liang R;Jang MJ;Zhong H;Dombeck D;von Zastrow M;Nimmerjahn A;Gradinaru V;Williams JT;Tian L
通讯作者:
Tian L
DOI:
10.1126/science.aac9462
发表时间:
2015-11-27
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Jiang X;Shen S;Cadwell CR;Berens P;Sinz F;Ecker AS;Patel S;Tolias AS
通讯作者:
Tolias AS
影响因子:
3.5
作者:
Chagas AM;Theis L;Sengupta B;Stüttgen MC;Bethge M;Schwarz C
通讯作者:
Schwarz C