Thymine hydroperoxide as a mediator in ionising radiation mutagenesis
Thymine hydroperoxide as a mediator in ionising radiation mutagenesis
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胸腺嘧啶氢过氧化物作为电离辐射诱变介质
作者:
H. Thomas;R. M. Herriott;B. Hahn;S. Y. Wang
WE describe the mutagenic action of chemically synthesised cis-5,6-dihydro-6-hydroperoxy-5-hydroxythymine (6-TOOH)1 on transforming DNA of Haemophilus influenzae2,3, and suggest a mechanism by which ionising radiation induces mutations in vivo.