Deformation and failure of cartilage in the tensile mode
Deformation and failure of cartilage in the tensile mode
复制标题
拉伸模式下软骨的变形和破坏
作者：
Y. Sasazaki;R. Shore;B. Seedhom
本研究的目的是可视化，在超微结构水平上，在拉伸模式下的软骨基质的变形和失效机制。采用成年牛制备全层哑铃形样本。有两个样本组;在“平行”组中，样本轴平行于定义关节面中胶原优先方向的分割线，在“垂直”组中，样本轴垂直于分割线。将样本放置在关节面最上方，并在单个微张力器械内经受一系列分级应变，同时使用体视显微镜和共聚焦激光扫描显微镜进行观察。然后用扫描电镜和透射电镜观察超微结构的变化。在拉伸模式下，软骨失效的机制包括以下阶段，无论应变是平行还是垂直于分裂线施加。(1)在0%应变下，关节面内的纤维网主要定向在分裂线方向。(2)随着应变的增加，纤维网变得更加取向的平行组和重新取向的垂直组中的方向施加的应变。(3)纤维网在施加应变的方向上完全重新定向后，失效的最初迹象是关节面内的纤维网破裂。(4)随后，破裂迅速扩展到更深层。更大的应变所需的纤维重新取向和完全断裂的“垂直组”比平行组。
The aim of this study was to visualize, at the ultrastructural level, the deformation and failure mechanism of cartilage matrix in the tensile mode. Full‐thickness dumbbell‐shaped specimens were prepared from adult bovines. There were two specimen groups; in the ‘parallel’ group the specimen axis was parallel to the split lines defining the preferential orientation of the collagen in the articular surface, and in the ‘perpendicular’ group the specimen axis was perpendicular to the split lines. Specimens were placed with the articular surface uppermost and subjected to a graded series of strain within individual mini‐tension devices, while observed with stereomicroscopy and confocal laser scanning microscopy. Thereafter, the changes in the ultrastructure were observed with both scanning and transmission electron microscopy. The mechanism of cartilage failure in the tensile mode comprised the following stages, whether the strain was applied parallel or perpendicular to the split line. (1) At 0% strain a fibrillar meshwork within the articular surface was predominantly orientated in the direction of the split line. (2) As strain increased, the fibrillar meshwork became more orientated in the parallel group and reorientated in the perpendicular group in the direction of the applied strain. (3) After complete reorientation of the fibrillar meshwork in the direction of the applied strain, the initial sign of failure was rupture of the fibrillar meshwork within the articular surface. (4) Subsequently, the rupture rapidly propagated into the deeper layers. Greater strains were required for fibrillar reorientation and complete rupture in the ‘perpendicular group’ than in the parallel group.
DOI：
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发表时间：
1983
期刊：
Bulletin of the Hospital for Joint Diseases Orthopaedic Institute
影响因子：
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作者：
Armstrong,CG;Mow,VC
通讯作者：
Mow,VC