Oculomotor synchronization of visual responses in modeled populations of retinal ganglion cells.
Oculomotor synchronization of visual responses in modeled populations of retinal ganglion cells.
复制标题
视网膜神经节细胞模型群体中视觉反应的动眼神经同步。
DOI：
10.1167/8.14.4
复制
发表时间：
2008
影响因子：
1.8
通讯作者：
Rucci,Michele
中科院分区：
文献类型：
--
作者：
Poletti,Martina;Rucci,Michele
我们最近已经表明，注视眼球运动提高了对被低频噪声掩盖的高空间频率光栅的方向的辨别力，但对被高频噪声掩盖的低频光栅没有帮助（M。鲁奇河Iovin，M. Poletti，& F. Santini，2007）。在这项研究中，我们探讨了负责这种现象的神经机制。小细胞神经节细胞模型的刺激，由相同的视觉输入所经历的受试者在我们的心理物理学实验，即，时空信号产生的眼睛运动过程中观看刺激。我们发现，在模型中的相关活动的空间组织预测实验中的受试者的表现。在观看高频光栅，固定眼球运动调制的方式依赖于细胞感受野的相对对齐的模型神经元的反应。只有当感受野平行于光栅的方向对齐时，反应才强烈地共变。这种对接收场对准轴的依赖性在观看低频光栅期间没有发生。在这种情况下，平行轴和正交轴上的细胞反应同样受到眼球运动的影响。这些结果支持了眼神经活动的同步在视网膜中的视觉信息的表示中的作用。
We have recently shown that fixational eye movements improve discrimination of the orientation of a high spatial frequency grating masked by low-frequency noise, but do not help with a low-frequency grating masked by high-frequency noise (M. Rucci, R. Iovin, M. Poletti, & F. Santini, 2007). In this study, we explored the neural mechanisms responsible for this phenomenon. Models of parvocellular ganglion cells were stimulated by the same visual input experienced by subjects in our psychophysical experiments, ie, the spatiotemporal signals resulting from viewing stimuli during eye movements. We show that the spatial organization of correlated activity in the model predicts the subjects' performance in the experiments. During viewing of high-frequency gratings, fixational eye movements modulated the responses of modeled neurons in a way that depended on the relative alignment of cell receptive fields. Responses covaried strongly only when receptive fields were aligned parallel to the grating's orientation. Such a dependence on the axis of receptive-field alignment did not occur during viewing of low-frequency gratings. In this case, the responses of cells on the parallel and orthogonal axes were similarly affected by eye movements. These results support a role for oculomotor synchronization of neural activity in the representation of visual information in the retina.