Pattern of rapid-eye movement sleep episode occurrence after an immobilization stress in the rat
Pattern of rapid-eye movement sleep episode occurrence after an immobilization stress in the rat
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DOI：
10.1016/j.neulet.2003.10.031
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发表时间：
2004-01-23
影响因子：
2.5
通讯作者：
Ramadan, W
中科院分区：
文献类型：
--
作者：
Dewasmes, G;Loos, N;Ramadan, W
大鼠的快速眼动睡眠(REMS)以发作的形式出现，间隔由长(>；3分钟：孤立的REMS发作，IREMSES)和短(<；3分钟：连续的REMS发作，SREMSES)间隔。聚集SREMSE的机制被认为更适合在其驱动力较高时增加REMS的量。我们在一种新的情况下测试了这一假设，方法是在适度的心理压力下暂时增强这种驱动力。在90分钟的束缚胁迫后，REMS比其余的黑暗时期增加了54%。这一增长与IREMSE的小幅增长(+40%)有关，但SREMSE的大幅增长(+300%)。因此，聚集REMS发作的机制是对在标准实验室条件下施加的适度心理应激的反应，而不是在睡眠剥夺之前。(C)2003爱思唯尔爱尔兰有限公司。保留所有权利。
Rapid-eye movement sleep (REMS) in the rat occur in the form of episodes separated by long (> 3 min: isolated REMS episodes, IREMSEs) and short (< 3 min: sequential REMS episodes, SREMSEs) intervals. The mechanism clustering SREMSEs is thought to be better suited to increase the amount of REMS when its drive is high. We tested this hypothesis in a new situation by transiently augmenting this drive with a moderate psychogenic stress. After a 90-mins immobilization stress, REMS increased by 54% over the rest of the dark phase. This increase was associated with a modest increase in IREMSEs (+40%), but a massive increase in SREMSEs (+300%). Thus, the mechanism that clusters REMS episodes operates in response to a moderate psychogenic stress imposed in standard laboratory conditions and not preceded by sleep deprivation. (C) 2003 Elsevier Ireland Ltd. All rights reserved.