Neutrophilic panniculitis associated with myelodysplastic syndrome/myeloproliferative neoplasm: a case report and literature review.
Neutrophilic panniculitis associated with myelodysplastic syndrome/myeloproliferative neoplasm: a case report and literature review.
复制标题
与骨髓增生异常综合征/骨髓增生性肿瘤相关的中性粒细胞性脂膜炎：病例报告和文献综述。
DOI：
10.1097/jd9.0000000000000286
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Nikbakht,Neda
中科院分区：
文献类型：
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作者：
Cohen,AlexaJ;Gleason,LauraK;Bhatti,SafiyyahA;Nikbakht,Neda
讨论：与其他嗜中性皮肤病相似，NP可能与骨髓来源的恶性血液病（如MDS/MPN）相关。文献综述显示，大多数MDS相关NP病例发生在MDS发作后，对全身性皮质类固醇有反应，而不是抗生素。感染应排除在开始治疗全身steroids.Conclusion：虽然机制仍然是未知的，重要的是临床医生要知道，NP与MDS，因此，血液恶性肿瘤应调查NP的诊断。一旦确诊，NP很容易治疗，对全身皮质类固醇有很好的反应。
Discussion:Similar to other neutrophilic dermatoses, NP may arise in association with hematologic malignancies of myeloid origin, such as MDS/MPN. A literature review revealed that most cases of NP associated with MDS occur after the onset of MDS and respond to systemic corticosteroids, not antibiotics. Infection should be ruled out before initiating treatment with systemic steroids.Conclusion:Although the mechanism is still unknown, it is important for clinicians to be aware that NP is associated with MDS; thus, hematological malignancies should be investigated on diagnosis of NP. Once diagnosed, NP is easily treated and has an excellent response to systemic corticosteroids.