Captive rhesus monkeys (Macaca mulatta) are commonly infected with Helicobacter cinaedi

Captive rhesus monkeys (Macaca mulatta) are commonly infected with Helicobacter cinaedi
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DOI:
10.1128/jcm.40.6.1908-1912.2002
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发表时间:
2002-06-01
影响因子:
9.4
通讯作者:
Solnick, JV
Solnick, JV
中科院分区:
医学2区
文献类型:
--
作者:
Fernandez, KR;Hansen, LM;Solnick, JV

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同性恋男性感染人类免疫缺陷病毒后,或者在其他免疫功能低下的宿主中,同性恋螺杆菌可能会引发直肠结肠炎或菌血症。有零星报道称从多种动物宿主中分离出同性恋螺杆菌,但到目前为止,仅发现仓鼠是常见的自然宿主。对16只无症状恒河猴(猕猴)的粪便进行微需氧培养,其中5只(31%)培养出弯曲的革兰氏阴性杆菌呈阳性。采用多相分类学方法将该微生物鉴定为同性恋螺杆菌。这些结果表明,同性恋螺杆菌经常在无症状的圈养恒河猴体内定植,这可能是人类感染的另一个潜在宿主来源。
Helicobacter cinaedi may cause proctocolitis or bacteremia in homosexual men infected with human immunodeficiency virus or occasionally in other immunocompromised hosts. There are scattered reports of H. cinaedi isolated from a variety of animal hosts, but to date only hamsters have been found to be a common natural reservoir. Microaerophillic cultures of feces from 5 of 16 asymptomatic rhesus monkeys (Macaca mulatta) (31%) were positive for a curved gram-negative rod. A polyphasic taxonomic approach was used to identify the organism as H. cinaedi. These results show that H. cinaedi frequently colonizes asymptomatic captive rhesus monkeys, which may serve as another potential reservoir for human infection.