XaaP-ing DPP8/9 for CARD8 activation.
XaaP-ing DPP8/9 for CARD8 activation.
复制标题
XaaP-ing DPP8/9 用于 CARD8 激活。
DOI:
10.1038/s41589-021-00958-5
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发表时间:
2022
影响因子:
14.8
通讯作者:
Mitchell,PatrickS
中科院分区:
文献类型:
--
作者:
Kulsuptrakul,Jessie;Mitchell,PatrickS
Inflammasomes are cytosolic immune complexes that initiate inflammatory signaling upon pathogen recognition. A new paper reveals that inhibition of M24B aminopeptidases drives the selective activation of the CARD8 inflammasome, providing new insights into its regulation.