Congenital Kyphosis by Segmentation Defect: Etiologic and Pathogenic Studies
Congenital Kyphosis by Segmentation Defect: Etiologic and Pathogenic Studies
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由节段缺陷引起的先天性脊柱后凸：病因学和病理学研究
DOI：
10.1097/01241398-198505000-00011
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发表时间：
1985
影响因子：
1.7
通讯作者：
D. Marton
中科院分区：
文献类型：
--
作者：
B. Morin;B. Poitras;M. Duhaime;C. Rivard;D. Marton
本文回顾了16例II型先天性后凸。作为一种有效的假设，我们假设这种病理应该具有类似于由于分割缺陷引起的脊柱侧凸的行为，如果存在真正的未分割棒。对不同参数的分析，包括受累节段的数量、患者的年龄、椎间盘受累程度和畸形部位，并没有证实这一假设。此外，一项实验动物研究未能重现这种先天性异常。我们认为，由“节段缺损”引起的后凸畸形代表了包括纤维环、环状突起和前纵韧带在内的椎周结构的发育缺陷，而不是真正的椎间筋。
Sixteen cases of type II congenital kyphosis were reviewed. As a working hypothesis, we assumed that this pathology should have a behavior similar to scoliosis due to a segmentation defect, if a true unsegmented bar existed. The analysis of different parameters including the number of levels involved, the patient's age, the degree of disc space involvement, and the site of deformity did not confirm this hypothesis. Furthermore, an experimental animal study failed to reproduce this congenital anomaly. It is our belief that kyphosis resulting from a “segmentation defect” represents a developmental defect of the perivertebral structures including the annulus fibrosus, the ring apophysis, and the anterior longitudinal ligament rather than a true intervertebral bar.