Electroencephalography (EEG) and event-related potentials (ERPs) with human participants.

Electroencephalography (EEG) and event-related potentials (ERPs) with human participants.
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DOI:
10.1002/0471142301.ns0625s52
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发表时间:
2010-07
影响因子:
--
通讯作者:
Braff, David L
Braff, David L
中科院分区:
其他
文献类型:
--
作者:
Light, Gregory A;Williams, Lisa E;Minow, Falk;Sprock, Joyce;Rissling, Anthony;Sharp, Richard;Swerdlow, Neal R;Braff, David L

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认知神经科学的一个基本目标是理解构成复杂高阶认知操作和功能域的基本神经过程。脑电图(EEG)是一种非侵入性和相对便宜的方法,用于评估神经生理功能,可用于实现这一目标。脑电图测量大脑中大量同步放电的神经元的电活动,电极放置在头皮上。本单元概述了设置与人类参与者的EEG实验的基础知识,包括设备,以及应用和准备电极帽的分步指南。还包括两个事件相关电位(ERP)范例,P50抑制和失配负性(MMN),这是早期感觉处理的措施的支持协议。这些范例可用于评估正常个体和临床人群(如精神分裂症患者)早期感觉处理的完整性。
Understanding the basic neural processes that underlie complex higher-order cognitive operations and functional domains is a fundamental goal of cognitive neuroscience. Electroencephalography (EEG) is a non-invasive and relatively inexpensive method for assessing neurophysiological function that can be used to achieve this goal. EEG measures the electrical activity of large, synchronously firing populations of neurons in the brain with electrodes placed on the scalp. This unit outlines the basics of setting up an EEG experiment with human participants, including equipment, and a step-by-step guide to applying and preparing an electrode cap. Also included are support protocols for two event-related potential (ERP) paradigms, P50 suppression and mismatch negativity (MMN), which are measures of early sensory processing. These paradigms can be used to assess the integrity of early sensory processing in normal individuals and clinical populations, such as individuals with schizophrenia.