An overview of COVID-19 in solid organ transplantation.
An overview of COVID-19 in solid organ transplantation.
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DOI：
10.1016/j.cmi.2022.02.005
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发表时间：
2022-06
期刊：
影响因子：
--
通讯作者：
van Duin D
中科院分区：
文献类型：
--
作者：
Bartelt L;van Duin D
COVID-19大流行在许多方面影响了实体器官移植（SOT）领域。2019冠状病毒病导致了方案的影响以及捐助者和受援者选择的变化。几项研究评估了SOT接受者COVID-19的病程、最佳治疗和预防。回顾SOT接受者中COVID-19的文献。检索了PubMed、Web of Science和Google Scholar。检索仅限于2019年1月1日至2021年12月1日期间发表的文章。COVID-19疫情最初导致实体器官移植数量减少。然而，大多数中心的移植量已经反弹。捐助者的选择仍然是一个没有完全界定的问题。一些报告表明，供体来源的SARS-CoV-2感染仅发生在肺移植受者中，来自SARS-CoV-2 PCR阳性供体的其他器官可能会安全使用。然而，这些数据仅限于病例系列。COVID-19感染后终末期肺病的移植越来越常见，并且已经取得了可接受的结果。在急性COVID-19中，移植候选人应在可行时延迟移植。调整后，SOT接受者的COVID-19后死亡率与普通人群相似，抗病毒和抗炎治疗选择的使用显著增加。预防COVID-19是SOT接受者的关键。SOT接受者和与SOT接受者接触的任何人的疫苗接种是预防的基石之一。非药物干预，如面部覆盖，手部卫生和身体距离仍然非常重要。COVID-19疫情继续对SOT候选人及受助人产生重大影响。预防感染是最重要的措施，需要仔细注意接种疫苗的方法，并传达持续需要面部覆盖物、身体距离和手部卫生的信息。
The COVID-19 pandemic has influenced the field of solid organ transplantation (SOT) in many ways. COVID-19 has led to programmatic impacts and changes in donor and recipient selection. Several studies have evaluated the course, optimal treatment, and prevention of COVID-19 in SOT recipients. To review the literature on COVID-19 in SOT recipients. PubMed, Web of Science, and Google Scholar were searched. The search was restricted to articles published between January 1, 2019 and December 1, 2021. The COVID-19 pandemic initially led to a decreased volume of solid organ transplants. However, transplant volumes at most centres have rebounded. Donor selection remains an incompletely defined issue. Several reports suggest that donor-derived SARS-CoV-2 infections occur only in lung transplant recipients and that other organs from SARS-CoV-2 PCR-positive donors could potentially be safely used. However, these data are limited to case series. Transplantation for end-stage lung disease after COVID-19 infection is increasingly common and has been performed with acceptable outcomes. In acute COVID-19 in a transplant candidate, transplantation should be delayed when feasible. After adjustment, mortality after COVID-19 appear similar in SOT recipients compared to the general population, with notable increased use of antiviral and anti-inflammatory treatment options. Prevention of COVID-19 is key in SOT recipients. Vaccination of SOT recipients and anyone who is in contact with SOT recipients is one of the cornerstones of prevention. Nonpharmacological interventions such as face coverings, hand hygiene, and physical distancing remain ever important as well. The COVID-19 pandemic continues to have an important impact on SOT candidates and recipients. Prevention of infection is the most important measure and requires careful attention to approaches to vaccination and messaging of the ongoing need for face coverings, physical distancing, and hand hygiene.
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与19009例相关急性呼吸衰竭患者的肺移植。
DOI：
10.7759/cureus.17152
发表时间：
2021-08
期刊：
Cureus
影响因子：
--
作者：
Sajid F;Ahmed T;Baz MA;Anstead MI
通讯作者：
Anstead MI
影响因子：
17.1
作者：
Bharat A;Querrey M;Markov NS;Kim S;Kurihara C;Garza-Castillon R;Manerikar A;Shilatifard A;Tomic R;Politanska Y;Abdala-Valencia H;Yeldandi AV;Lomasney JW;Misharin AV;Budinger GRS
通讯作者：
Budinger GRS
影响因子：
10.7
作者：
COVIDSurg Collaborative;GlobalSurg Collaborative
通讯作者：
GlobalSurg Collaborative
影响因子：
8.8
作者：
Chaudhry, Zohra S.;Williams, Jonathan D.;Alangaden, George J.
通讯作者：
Alangaden, George J.
影响因子：
8.8
作者：
Fung, Monica;Chiu, Charles Y.;Babik, Jennifer M.
通讯作者：
Babik, Jennifer M.