Finite element analysis applied to cornea reshaping -: art. no. 064018
Finite element analysis applied to cornea reshaping -: art. no. 064018
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DOI：
10.1117/1.2136149
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发表时间：
2005-11-01
影响因子：
3.5
通讯作者：
Juhasz, T
中科院分区：
文献类型：
--
作者：
Fernández, DC;Niazy, AM;Juhasz, T
建立了角膜的二维有限元模型，以模拟角膜重塑及其由屈光手术引起的变形。在数值模拟中，线性和非线性弹性模型时，刚度随深度变化的不均匀性考虑。创建多个模拟，其采用不同的几何配置来去除角膜组织。并排比较不同的本构关系。为了便于比较，材料性能常数确定从相同的实验数据，这是从角膜条和膜膨胀实验的机械测试获得。然后，我们通过比较计算的屈光力变化与临床结果来验证所产生的模型。使用有限元模拟角膜组织切除产生的组织变形与临床观察到的术后结果一致。当角膜的硬度不均匀性和变形的非线性被包括在模拟中时，开发的模型提供了一个更可预测的屈光结果。有限元分析是一种有用的工具，用于模拟手术对角膜的影响，并更好地了解角膜的生物力学。患者特定模拟的创建将允许基于个性化有限元模型预测手术结果。(C)2005年，由光学仪器工程师学会（Society of Photo-Optical Instrumentation Engineers）主办。
A 2-D finite element model of the cornea is developed to simulate corneal reshaping and the resulting deformation induced by refractive surgery. In the numerical simulations, linear and nonlinear elastic models are applied when stiffness inhomogeneities varying with depth are considered. Multiple simulations are created that employ different geometric configurations for the removal of the corneal tissue. Side-by-side comparisons of the different constitutive laws are also performed. To facilitate the comparison, the material property constants are identified from the same experimental data, which are obtained from mechanical tests on corneal strips and membrane inflation experiments. We then validate the resulting models by comparing computed refractive power changes with clinical results. Tissue deformations created by simulated corneal tissue removal using finite elements are consistent with clinically observed postsurgical results. The model developed provides a much more predictable refractive outcome when the stiffness inhomogeneities of the cornea and non-linearities of the deformations are included in the simulations. Finite element analysis is a useful tool for modeling surgical effects on the cornea and developing a better understanding of the biomechanics of the cornea. The creation of patient-specific simulations would allow surgical outcomes to be predicted based on individualized finite element models. (C) 2005 Society of Photo-Optical Instrumentation Engineers.