Antifungal spectrum of flavone and flavanone tested against 34 different fungi

Antifungal spectrum of flavone and flavanone tested against 34 different fungi
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DOI:
10.1017/s0953756296003322
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发表时间:
1997-06-01
影响因子:
--
通讯作者:
Jha, HC
Jha, HC
中科院分区:
其他
文献类型:
--
作者:
Weidenborner, M;Jha, HC

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在0.5、2和8 × 10 ~(-4)M三种不同浓度下,对34种真菌进行了黄酮和黄烷酮的抗真菌活性测试。总的来说,黄酮类化合物是活性较高的物质,在2 × 10(-4)M浓度下对几种真菌都有完全抑制作用。对某些真菌的抑菌活性与浓度之间不存在线性关系。球毛壳菌是唯一能被8 × 10 ~(-4)M黄烷酮完全抑制的真菌。然而,几种真菌在2 × 10(-4)M时确实显示出较高的抑制率。
The antifungal activity of flavone and flavanone was tested in three different concentrations, 0.5, 2 and 8 x 10(-4) M, against 34 fungi. In general, flavone was the substance with the higher activity, and could at 2 x 10(-4) M completely inhibit several fungi. No linear relationships between the concentration and the antifungal activity could be observed for some fungi. Chaetomium globosum was the only fungus which was totally inhibited by flavanone at 8 x 10(-4) M. Several fungi did, however, show a higher inhibition rate at 2 x 10(-4) M.