Colloidosomes as a Protocell Model: Engineering Life-Like Behaviour through Organic Chemistry
Colloidosomes as a Protocell Model: Engineering Life-Like Behaviour through Organic Chemistry
复制标题
胶体体作为原始细胞模型：通过有机化学设计类生命行为
DOI：
10.1002/ejoc.202200968
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发表时间：
2022
影响因子：
2.8
通讯作者：
Park J
中科院分区：
文献类型：
--
作者：
Park J
The bottom‐up synthesis of self‐assembled micro‐compartmentalised systems that mimic basic characteristics of living cells is rapidly evolving. These types of systems are termed “protocells” and can be chemically programmed to grow and divide, to send and receive chemical signals, to transcript and translate chemical information, to adhere to surfaces or to other protocells, and to perform rudimental enzyme‐mediated metabolic processes. An emerging protocell model that is attracting great attention is the colloidosome. Colloidosomes are microcapsules with a chemically crosslinked, semipermeable membrane composed of amphiphilic nanoparticles. Colloidosomes display important advantages over other protocell models (e. g., vesicles and coacervate micro‐droplets) due to their physical‐chemical properties that can be easily tuned through the careful engineering of their synthetic building blocks. In this review, we deliver an overview of the different types of colloidosomes that have been developed thus far and discuss how organic chemistry contributes to the design and bottom‐up synthesis of novel types of colloidosomes endowed with advanced chemically programmed bio‐inspired functions.
