The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia
The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia
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DOI：
10.1016/j.ijnurstu.2003.07.001
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发表时间：
2004-03-01
影响因子：
8.1
通讯作者：
Lu, RB
中科院分区：
文献类型：
--
作者：
Chou, KR;Chen, R;Lu, RB
本研究旨在探讨尼古丁贴片疗法对精神分裂症患者戒烟的疗效。这是一项纵向研究，68名精神分裂症患者被分配到为期8周的尼古丁贴片治疗计划或对照组。广义估计方程分析显示，在8周的尼古丁贴片治疗和3个月的随访中，受试者的尼古丁依赖(Fagerstrom耐受性问卷)、每天吸烟数量和一氧化碳水平显著降低。8周戒烟率为26.9%，随访3个月戒烟率为26.9%。在3个月的随访中，尼古丁贴片组的持续戒烟率为23.1%。(C)2003爱思唯尔有限公司。保留所有权利。
The purpose of this study was to determine the effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia. This was a longitudinal study and sixty-eight schizophrenic patients were assigned to 8 weeks of a nicotine-patch therapy program or a control group. The generalized estimating equation analysis revealed that there were significant reductions in the subjects' nicotine dependence (Fagerstrom Tolerance Questionnaire), the number of cigarettes per day, and CO levels over an 8-week period of nicotine-patch therapy and 3-month follow-up. The point-prevalence rates of abstinence from smoking were an abstinence of 26.9% at 8 weeks and 26.9% at a 3-month follow-up. At the 3-month follow-up, the rate of continuous smoking abstinence in the nicotine-patch group was 23.1%. (C) 2003 Elsevier Ltd. All rights reserved.