Transmission dynamics of an emerging infectious disease in wildlife through host reproductive cycles
Transmission dynamics of an emerging infectious disease in wildlife through host reproductive cycles
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DOI：
10.1038/ismej.2010.123
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发表时间：
2011-02-01
期刊：
影响因子：
11
通讯作者：
Kawabata, Zen'ichiro
中科院分区：
文献类型：
--
作者：
Uchii, Kimiko;Telschow, Arndt;Kawabata, Zen'ichiro
新出现的传染病是对野生动物种群的主要威胁。为了提高我们对这些疾病的动态的理解，我们研究了宿主繁殖行为和季节性温度变化如何驱动野生宿主之间的感染传播，使用鲤鱼疱疹病毒3型（CyHV-3）疾病的模型系统。我们的主要发现如下：（1）血清阳性率调查显示，CyHV-3感染主要发生在成年宿主中，（2）CyHV-3在宿主种群中的定量检测表明，CyHV-3在春季宿主繁殖和水温升高时最丰富;（3）CyHV-3在水中的动态分析表明，CyHV-3在宿主种群中的数量最多。3浓度在繁殖生境中显著增加，在主机组交配。这些结果表明，繁殖栖息地可以成为传染病传播的热点，如果主机聚集交配和病原体的激活发生在主机繁殖季节。The ISME Journal（2011）5，244-251; doi：10.1038/ismej.2010.123; 2010年8月26日在线发表
Emerging infectious diseases are major threats to wildlife populations. To enhance our understanding of the dynamics of these diseases, we investigated how host reproductive behavior and seasonal temperature variation drive transmission of infections among wild hosts, using the model system of cyprinid herpesvirus 3 (CyHV-3) disease in common carp. Our main findings were as follows: (1) a seroprevalence survey showed that CyHV-3 infection occurred mostly in adult hosts, (2) a quantitative assay for CyHV-3 in a host population demonstrated that CyHV-3 was most abundant in the spring when host reproduction occurred and water temperature increased simultaneously and (3) an analysis of the dynamics of CyHV-3 in water revealed that CyHV-3 concentration increased markedly in breeding habitats during host group mating. These results indicate that breeding habitats can become hot spots for transmission of infectious diseases if hosts aggregate for mating and the activation of pathogens occurs during the host breeding season. The ISME Journal (2011) 5, 244-251; doi:10.1038/ismej.2010.123; published online 26 August 2010