EPIDEMIC DENGUE-3 IN CENTRAL JAVA, ASSOCIATED WITH LOW VIREMIA IN MAN
EPIDEMIC DENGUE-3 IN CENTRAL JAVA, ASSOCIATED WITH LOW VIREMIA IN MAN
复制标题
DOI：
10.4269/ajtmh.1981.30.1094
复制
发表时间：
1981-01-01
影响因子：
3.3
通讯作者：
GUNARSO, S
中科院分区：
文献类型：
--
作者：
GUBLER, DJ;SUHARYONO, W;GUNARSO, S
1978年在印度尼西亚中爪哇省研究了3型登革热的暴发。与之前在爪哇中部和东部发生的登革热3型疫情相比，这次疫情的爆发性较低，与轻度疾病和低病毒血症有关。血清学确诊患者的登革热病毒分离率仅为32%，而一年前班图尔疫情的分离率为65%。无论是登革热血凝抑制抗体滴度，也没有一天的疾病，标本收集占这种差异。登革病毒的一些自然发生的毒株（地方性毒株）显然与低病毒血症有关，通常仅引起人类轻度疾病。
An outbreak of dengue type 3 was studied in Central Java, Indonesia, in 1978. In contrast to previous dengue 3 epidemics in Central and East Java, this outbreak was less explosive and was associated with mild illness and low viremia. The dengue virus isolation rate from serologically confirmed patients was only 32% compared to 65% for an epidemic in Bantul 1 yr earlier. Neither dengue hemagglutination-inhibition antibody titers nor day of illness on which specimens were collected accounted for this difference. Some naturally occurring strains of dengue virus (endemic strains) evidently are associated with low viremia and generally cause only mild illness in man.