Worldwide survey of IVF practices: trigger, retrieval and embryo transfer techniques
Worldwide survey of IVF practices: trigger, retrieval and embryo transfer techniques
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DOI：
10.1007/s00404-014-3232-6
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发表时间：
2014-09-01
影响因子：
2.6
通讯作者：
Shoham, Zeev
中科院分区：
文献类型：
--
作者：
Tobler, Kyle J.;Zhao, Yulian;Shoham, Zeev
从广泛分布的全球调查中确定体外受精（IVF）提供者使用的共同和不同的实践模式。关于临床IVF实践涉及卵母细胞成熟触发，卵母细胞回收和胚胎移植的具体信息被引出。这是一项基于互联网的全球试管婴儿实践问卷研究。我们使用了26道关于常见临床实践的选择题。报告的数据是根据在特定试管婴儿中心进行的试管婴儿周期的数量加权的，由单个应答者代表。调查在全球71个国家的359个中心完成。确定的最常见的实践模式（定义为千分之75%的试管婴儿周期）包括：使用人绒毛膜促性腺激素（hCG）作为拮抗剂方案的触发，从hCG触发到卵母细胞回收没有常规患者监测，在卵母细胞成熟触发后34-37小时进行卵母细胞回收，使用单腔回收针，在患者出院前卵母细胞回收后没有常规检查，使用超声辅助胚胎移植。这是针对卵母细胞成熟触发、卵母细胞回收和胚胎移植的具体试管婴儿实践的最大和最多样化的调查。确定了几种与循证医学相关的统一实践模式；然而，我们确定了多个变量的实践模式，这可能是由于缺乏明确的证据来指导试管婴儿从业者。这项调查的结果允许试管婴儿提供者将他们的具体实践模式与全球不同人口的试管婴儿提供者进行比较。
To identify common and varying practice patterns used by in vitro fertilization (IVF) providers from a broadly distributed, worldwide survey. Specific information regarding clinical IVF practices involving the oocyte maturation triggering, oocyte retrieval and embryo transfer was elicited.This is an internet-based questionnaire study of IVF practices throughout the world. We used 26 multiple choice questions regarding common clinical practices. The data reported are weighted based on the number of IVF cycles performed at the specific IVF center, represented by a single respondent.Surveys were completed from 359 centers in 71 countries throughout the world. The most common practice patterns (defined as a parts per thousand yen75 % of IVF cycles) identified included: use of human chorionic gonadotropin (hCG) for trigger with an antagonist protocol, no routine patient monitoring from hCG trigger to oocyte retrieval, timing oocyte retrieval 34-37 h following oocyte maturing trigger, use of a single lumen retrieval needle, no routine tests following oocyte retrieval prior to patient discharge and use of ultrasound assistance with embryo transfer.This is the largest and most diversely represented survey of specific IVF practices addressing oocyte maturation triggers, oocyte retrieval and embryo transfers. Several uniform practice patterns were identified that can be correlated with evidence-based medicine; however, we identified multiple variable practice patterns which is likely the result of the absence of definitive evidence to guide IVF practitioners. The results of this survey allow IVF providers to compare their specific practice patterns with those of a global diverse population of IVF providers.