The Brain-Gut Axis in Health and Disease
The Brain-Gut Axis in Health and Disease
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DOI：
10.1007/978-1-4939-0897-4_6
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发表时间：
2014-01-01
期刊：
影响因子：
--
通讯作者：
Aziz, Qasim
中科院分区：
文献类型：
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作者：
Al Omran, Yasser;Aziz, Qasim
大脑和肠道之间的相互作用已经被认识了好几个世纪。这种双向相互作用通过神经、免疫和激素途径发生，不仅对正常的胃肠道功能很重要，而且在形成高级认知功能（如我们的感觉和潜意识决策）方面也起着重要作用。因此，正常信号的扰动与多种疾病有关，包括炎症性和功能性胃肠道疾病以及饮食失调，这一点并不奇怪。
The interaction between the brain and the gut has been recognized for many centuries. This bidirectional interaction occurs via neural, immunological and hormonal routes, and is important not only in normal gastrointestinal function but also plays a significant role in shaping higher cognitive function such as our feelings and our subconscious decision-making. Therefore, it remains unsurprising that perturbations in normal signalling have been associated with a multitude of disorders, including inflammatory and functional gastrointestinal disorders, and eating disorders.