Co-morbid disorders and sexual risk behavior in Nigerian adolescents with bipolar disorder.
Co-morbid disorders and sexual risk behavior in Nigerian adolescents with bipolar disorder.
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DOI：
10.1186/1755-7682-2-16
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发表时间：
2009-06-01
期刊：
影响因子：
--
通讯作者：
Okonkwo, Kevin O
中科院分区：
文献类型：
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作者：
Bakare, Muideen O;Agomoh, Ahamefule O;Okonkwo, Kevin O
背景：青春期起病的双相情感障碍常伴有精神活性物质使用障碍。躁狂症状和共病的精神活性物质使用障碍容易使患有双相情感障碍的青少年冲动、判断受损和冒险行为，其中往往包括性风险行为。在尼日利亚，关于青春期起病双相情感障碍的共病障碍和性危险行为的模式的信息很缺乏。本研究评估双相情感障碍青少年共病障碍的患病率和模式，并确定性行为危险行为的相关因素。方法：采用社会人口学问卷调查青少年的社会人口学信息。通过临床访谈、体格检查和实验室调查，在一年的门诊随访中确定这些青少年的共病障碍。结果：在一年的时间里，共对46例双相情感障碍青少年进行了随访。22例(47.8%)青少年合并有大麻使用障碍、酒精使用障碍、品行障碍和HIV感染，分别占23.9%、8.7%、13.0%和2.2%。21例(45.7%)青少年有阳性性行为史，这与共病障碍的存在(p=0.003)、青少年的宗教活动水平(p=0.000)、父母的婚姻状况(p=0.021)显著相关。结论：在对双相情感障碍儿童和青少年进行干预时，应特别关注具有共病障碍、冲动倾向和性行为倾向的青少年群体。这可能有助于改善这一青少年群体的长期结局。
BACKGROUND: Adolescent onset bipolar disorder often presents with co-morbid disorders of which psychoactive substance use disorders are notable. Mania symptoms and co-morbid psychoactive substance use disorders prone adolescents with bipolar disorder to impulsivity, impaired judgment, and risk taking behavior which often includes sexual risk behavior. There are dearth of information on pattern of co-morbid disorders and sexual risk behavior in adolescent onset bipolar disorder in Nigeria. This study assessed the prevalence and pattern of co-morbid disorders and determined associated factors of sexual risk behavior among adolescents with bipolar disorder.METHODS: Socio-demographic information was obtained from the adolescents using socio-demographic questionnaire. Clinical interview, physical examination and laboratory investigations were employed to establish co-morbid disorders in these adolescents during the outpatient follow up visits over a one year period.RESULTS: A total of forty six (46) adolescents with bipolar disorder were followed up over a one year period. Twenty two (47.8%) of the adolescents had co-morbid disorders with cannabis use disorders, alcohol use disorders, conduct disorder with or without other psychoactive substance use accounting for 23.9%, 8.7%, 13.0% respectively and HIV infection, though a chance finding accounting for 2.2%. Twenty one (45.7%) of the adolescents had positive history of sexual risk behavior, which was significantly associated with presence of co-morbid disorders (p = 0.003), level of religion activities in the adolescents (p = 0.000), and marital status of the parents (p = 0.021).CONCLUSION: When planning interventions for children and adolescents with bipolar disorder, special attention may need to be focused on group of adolescents with co-morbid disorders and propensity towards impulsivity and sexual risk behavior. This may help in improving long term outcome in this group of adolescents.