Introduction to genetic association studies.
Introduction to genetic association studies.
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DOI：
10.1101/pdb.top068163
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发表时间：
2012-03-01
影响因子：
--
通讯作者：
Knight, Jo
中科院分区：
文献类型：
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作者：
Lewis, Cathryn M;Knight, Jo
遗传关联研究用于通过测试疾病状态和遗传变异之间的相关性来寻找导致特定疾病的候选基因或基因组区域。本文概述了此类研究的设计和分析，重点关注候选基因或区域的病例对照研究。
Genetic association studies are used to find candidate genes or genome regions that contribute to a specific disease by testing for a correlation between disease status and genetic variation. This article provides a broad outline of the design and analysis of such studies, focusing on case-control studies in candidate genes or regions.