Cerebral autoregulation and anesthesia
Cerebral autoregulation and anesthesia
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DOI：
10.1097/aco.0b013e32833020be
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发表时间：
2009-10-01
影响因子：
2.5
通讯作者：
Lam, Arthur M.
中科院分区：
文献类型：
--
作者：
Dagal, Armagan;Lam, Arthur M.
综述的目的本文将回顾近年来有关麻醉和监测技术与脑自动调节的文献。我们将讨论生理和药理因素对脑自动调节的影响及其临床相关性与新的evidence.Recent findingsIntravenous麻醉，如丙泊酚和瑞芬太尼的组合，提供了最好的保存自动调节的帮助。在吸入剂七氟醚似乎保留自动调节在所有剂量，而与其他代理autoregulation受损的剂量相关mannes.SummaryIntraoperative脑自动调节监测是一个重要的考虑因素，神经系统疾病的患者。基于经颅多普勒的静态自动调节测量似乎是用于此目的的最稳健的床边方法。
Purpose of reviewThis review will examine the recent literature on anesthesia and monitoring techniques in relation to cerebral autoregulation. We will discuss the effect of physiologic and pharmacological factors on cerebral autoregulation alongside its clinical relevance with the help of new evidence.Recent findingsIntravenous anesthesia, such as combination of propofol and remifentanil, provides best preservation of autoregulation. Among inhaled agents sevoflurane appears to preserve autoregulation at all doses, whereas with other agents autoregulation is impaired in a dose-related manner.SummaryIntraoperative cerebral autoregulation monitoring is an important consideration for the patients with neurologic disease. Transcranial Doppler based static autoregulation measurements appears to be the most robust bedside method for this purpose.