SUDEP: Overview of definitions and review of incidence data
SUDEP: Overview of definitions and review of incidence data
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DOI：
10.1053/seiz.1999.0306
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发表时间：
1999-09-01
影响因子：
3
通讯作者：
Coan, SP
中科院分区：
文献类型：
--
作者：
Annegers, JF;Coan, SP
癫痫患者突然意外和不明原因死亡（SUDEP）的分类、发生率和预测因素在过去几年中受到了相当大的关注。明确的，很可能的，可能的，和不SUDEP的分类在美国流行病学研究的具体标准。SUDEP在不同癫痫人群中的发病率。SUDEP是一种真实的现象，因为癫痫患者的这种死亡发生率（尤其是在相对年轻的年龄）远远高于非癫痫患者（可能是40倍）。SUDEP发生率在基于人群的研究中较低，在转诊人群和复杂部分性癫痫辅助药物临床试验中较高，在手术系列中最高。癫痫发作的严重程度似乎是SUDEP最强的危险因素，因为在难治性癫痫患者的研究中报告了更高的发生率。其他潜在的危险因素，包括性别，癫痫病因，发病年龄较小，部分发作癫痫，尚未解决。(C)1999年，深圳市华丰贸易有限公司
The classification, occurrence, and predictors of sudden unexpected and unexplained death in individuals with epilepsy (SUDEP) have received considerable attention over the last few years. Specific criteria for the classification of definite, probable, possible, and not SUDEP implemented in United States epidemiologic studies are presented. The incidence of SUDEP in different epilepsy populations is presented. SUDEP is a real phenomenon, because the occurrence of such deaths, especially at relatively young ages, among individuals with epilepsy is far greater (perhaps 40-fold) than among those without epilepsy. SUDEP incidence rates are lower in population-based studies, higher in referral populations and clinical trials of adjunct drugs for complex partial epilepsy, and highest for surgical series. Seizure severity appears to be the strongest risk factor for SUDEP because higher rates are reported from studies of individuals with intractable epilepsy. Other potential risk factors, including sex, seizure etiology, younger age at onset, and partial-onset seizures, are unresolved. (C) 1999 BEA Trading Ltd.