Serum interieukin-11 in patients with benign prostatic hyperplasia and prostate cancer

Serum interieukin-11 in patients with benign prostatic hyperplasia and prostate cancer
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DOI:
10.1007/s11255-004-6086-1
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发表时间:
2005-01-01
影响因子:
2
通讯作者:
Fuse, Hideki
Fuse, Hideki
中科院分区:
医学4区
文献类型:
--
作者:
Furuya, Yuzo;Nishio, Remon;Fuse, Hideki

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为了阐明血清白细胞介素-11(IL-11)水平是否可以作为前列腺癌患者的有用标志物,在治疗前分别测定了73例前列腺癌和23例良性前列腺增生(BPH)患者的血清IL-11。前列腺癌与BPH患者血清IL-11水平差异无统计学意义。与未经治疗的癌症患者相比,具有抗前列腺癌的患者具有显著更高水平的IL-11。血清IL-11水平可能是前列腺癌进展的潜在肿瘤标志物。
To clarify whether serum levels of interleukin-11 (IL-11) could be a useful marker in patients with prostate cancer, serum IL-11 was determined in 73 and 23 men with prostate cancer and benign prostate hyperplasia (BPH), respectively, before treatment. There were no statistical differences of IL-11 levels between patients with prostate cancer and BPH. Patients with hormone-resistant prostate cancer had a significantly higher level of IL-11 than those with untreated cancer. Serum IL-11 levels may be a potential tumor marker for prostate cancer progression.