A pediatric ventricular assist device: its development and experimental evaluation of hemodynamic effects on postoperative heart failure of congenital heart diseases.

A pediatric ventricular assist device: its development and experimental evaluation of hemodynamic effects on postoperative heart failure of congenital heart diseases.
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小儿心室辅助装置的研制及对先天性心脏病术后心力衰竭血流动力学影响的实验评价。

DOI:
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发表时间:
2008
期刊:
影响因子:
2.4
通讯作者:
M. Kinoshita
M. Kinoshita
中科院分区:
工程技术3区
文献类型:
--
作者:
Y. Taenaka;H. Takano;H. Noda;M. Kinoshita

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为了评价小儿心室辅助装置(VAD)的有效性,在两种类型的先天性心脏病术后严重心力衰竭模型上实验研究了VAD的血流动力学效应。在模型I Fontan或改良Fontan手术模型中,在4只犬中通过手术排除右心室泵功能,并在右心房和肺动脉之间构建分流。在左心房和主动脉之间放置VAD,肺内压差和心输出量增加。模型Ⅱ:5只犬手术诱导右心衰竭,并注射玻璃珠造成高肺血管阻力。当右心房和肺动脉干之间的VAD被激活时,心输出量增加,右心房压力降低。总之,VAD将成为一种有前途的方式来管理儿科严重心力衰竭病例。
To evaluate the effectiveness of a pediatric ventricular assist device (VAD), hemodynamic effects of the VAD were investigated experimentally in two types of postoperative profound heart failure models of congenital heart disease. In the model I Fontan or modified Fontan operation model, right ventricular pump function was excluded surgically and a shunt between the right atrium and the pulmonary artery was constructed in four dogs. With a VAD between the left atrium and the aorta, pressure gradient across the lung and the cardiac output increased. Right ventricular failure was induced surgically and high pulmonary vascular resistance was made by injection of glass beads in five dogs in model II. Cardiac output increased and the right atrial pressure decreased when a VAD between the right atrium and the pulmonary arterial trunk was activated. In conclusion, the VAD will become a promising modality to manage pediatric profound heart failure cases.
DOI: --
发表时间: 1980
期刊: Transactions - American Society for Artificial Internal Organs
影响因子: --
作者:
PaeJr,WE;Rosenberg,G;Donachy,JH;Landis,DL;Phillips,WM;Parr,GV;Prophet,GA;Pierce,WS
通讯作者: Pierce,WS
DOI: --
发表时间: 1987
期刊: ASAIO transactions
影响因子: --
作者:
Whalen,RL;Hurford,WE;Skoskiewicz,M;Wonders,TR;Zapol,WM
通讯作者: Zapol,WM