If You'd Like to Stop a Type III CRISPR Ribonuclease, Then You Should Put a Ring (Nuclease) on It.
If You'd Like to Stop a Type III CRISPR Ribonuclease, Then You Should Put a Ring (Nuclease) on It.
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如果您想停止 III 型 CRISPR 核糖核酸酶,那么您应该在其上放置一个环(核酸酶)。
DOI:
10.1016/j.molcel.2018.10.048
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发表时间:
2018
期刊:
影响因子:
16
通讯作者:
Marraffini,LucianoA
中科院分区:
文献类型:
--
作者:
Mo,CharlieY;Marraffini,LucianoA
Athukoralage et al. (2018) identify a new class of nuclease that degrades cyclic oligoadenylate (cOA), a second messenger that activates non-specific RNA degradation by the type III CRISPR-Cas accessory RNase Csm6/Csx1. This discovery provides a mechanism for regulating the degradation of foreign transcripts during the type III CRISPR immune response.
影响因子:
64.8
作者:
Athukoralage JS;Rouillon C;Graham S;Grüschow S;White MF
通讯作者:
White MF