Differential brain growth in the infant born preterm: Current knowledge and future developments from brain imaging
Differential brain growth in the infant born preterm: Current knowledge and future developments from brain imaging
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DOI：
10.1016/j.siny.2005.05.003
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发表时间：
2005-10-01
影响因子：
3
通讯作者：
Boardman, JP
中科院分区：
文献类型：
--
作者：
Counsell, SJ;Boardman, JP
早产与儿童期和青少年期神经精神损害的高患病率相关，但这些疾病背后的神经相关性尚未完全了解。定量磁共振成像技术已被用于研究早产或极低出生体重的儿童和青少年大脑生长和发育的细微差异。扩散张量成像和计算机辅助形态测量技术（包括基于体素的形态测量和基于变形的形态测量）已经确定了不同年龄早产幸存者的组织微结构和脑形态的异常，其中一些改变具有特定的功能相关性。本章回顾了早产后不同脑发育的文献报道，重点是与神经精神损害相关的形态学变化。(c)2005爱思唯尔有限公司保留所有权利。
Preterm birth is associated with a high prevalence of neuropsychiatric impairment in childhood and adolescence, but the neural correlates underlying these disorders are not fully understood. Quantitative magnetic resonance imaging techniques have been used to investigate subtle differences in cerebral growth and development among children and adolescents born preterm or with very low birth weight. Diffusion tensor imaging and computer-assisted morphometric techniques (including voxel-based morphometry and deformation-based morphometry) have identified abnormalities in tissue microstructure and cerebral morphology among survivors of preterm birth at different ages, and some of these alterations have specific functional correlates. This chapter reviews the literature reporting differential brain development following preterm birth, with emphasis on the morphological changes that correlate with neuropsychiatric impairment. (c) 2005 Elsevier Ltd. All rights reserved.