Longitudinal study of Borrelia burgdorferi infection in New Jersey outdoor workers, 1988-1991.
Longitudinal study of Borrelia burgdorferi infection in New Jersey outdoor workers, 1988-1991.
复制标题
新泽西州户外工作者伯氏疏螺旋体感染的纵向研究，1988-1991 年。
DOI：
10.1093/oxfordjournals.aje.a117033
复制
发表时间：
1994
影响因子：
5
通讯作者：
Childs,JE
中科院分区：
文献类型：
--
作者：
Schwartz,BS;Goldstein,MD;Childs,JE
From 1988 to 1991, annual questionnaires and serosurveys were performed in a cohort of outdoor workers in New Jersey at high risk for Lyme disease to 1) evaluate temporal trends in seroprevalence and seroconversion of antibody toBorrelia burgdorferi; 2) identify risk factors forB.burgdorferiseroconversion during these years; and 3) examine associations between such seroconversion in 1989–1990 and anti-tick saliva antibody (ATSA, a biologic marker of tick exposure) seropositivity in 1990. A total of 1,519 workers participated in at least 1 year of the study. Lyme disease seroprevalence and seroconversion increased from 1988 to 1990 and then decreased in 1991. Years at residence, rural residence, and a history of medical problems were observed to be risk factors for seroconversion from 1988 to 1991. An interaction between pet ownership and rural residence was observed in that rural residents were only at an elevated risk if they owned pets.B. burgdorferiseroconversion from 1989 to 1990 was associated with ATSA seropositivity in 1990; in subjects reporting low tick exposure, the odds ratio was 8.2 (95% confidence interval 1.5–44.7). Associations between ATSA andB. burgdorferiserologic status suggested that educational programs may have contributed to the decline in Lyme seroprevalence and seroconversion in 1991.
