GENERALIZED EQUATIONS FOR THE ANALYSIS OF INHIBITIONS OF MICHAELIS-MENTEN AND HIGHER-ORDER KINETIC SYSTEMS WITH 2 OR MORE MUTUALLY EXCLUSIVE AND NON-EXCLUSIVE INHIBITORS

GENERALIZED EQUATIONS FOR THE ANALYSIS OF INHIBITIONS OF MICHAELIS-MENTEN AND HIGHER-ORDER KINETIC SYSTEMS WITH 2 OR MORE MUTUALLY EXCLUSIVE AND NON-EXCLUSIVE INHIBITORS
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DOI：
10.1111/j.1432-1033.1981.tb06218.x
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发表时间：
1981-01-01
期刊：
EUROPEAN JOURNAL OF BIOCHEMISTRY
影响因子：
--
通讯作者：
TALALAY, P
TALALAY, P
中科院分区：
其他
文献类型：
--
作者：
CHOU, TC;TALALAY, P

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给出了一个不含底物（Km）或抑制剂（Ki）动力学常数的简单通用方程。它描述了两种互斥的可逆抑制剂对遵循Michaelis-Menten动力学的酶系统的影响的总和。
A simple and generalized equation not involving kinetic constants for substrates (Km) or inhibitors (Ki) is given. It describes the summation of the effects of 2 mutually exclusive and reversible inhibitors on enzyme systems obeying Michaelis-Menten kinetics.