Clinical relevance of short-term day-time breathing disorders in chronic heart failure patients
Clinical relevance of short-term day-time breathing disorders in chronic heart failure patients
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DOI：
10.1016/j.ejheart.2007.06.009
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发表时间：
2007-09-01
影响因子：
18.2
通讯作者：
Sleight, Peter
中科院分区：
文献类型：
--
作者：
La Rovere, Maria Teresa;Pinna, Gian Domenico;Sleight, Peter
背景：周期性呼吸（PB，潮气量的增减，其中换气过度与呼吸暂停或呼吸不足交替出现）在心力衰竭 (HF) 患者的睡眠和清醒期间很常见，并且可能会增加死亡率。目的：评估短期日间 PB 对心力衰竭患者预后的影响。方法：我们前瞻性研究了 380 名连续 HF 转诊患者，这些患者进行了 10 分钟的仰卧日间呼吸录音。在中位随访 41 个月期间，我们将 PB（根据已知预测因子进行调整）与总心脏死亡率相关联。 结果：145/380 名患有更严重心衰和左心室功能受损的患者出现了日间 PB（p
Background: Periodic Breathing (PB, waxing and waning of tidal volume in which hyperventilation alternates with periods of apnoea or hypopnoea), is common during sleep and wakefulness in patients with Heart Failure (HF) and may increase mortality.Aim: To assess the effect of short-term, day-time PB on prognosis, in HF patients.Methods: We prospectively studied 380 consecutive HF referrals who had a 10 min, supine day-time respiratory recording. We related PB (adjusted for known predictors) to total cardiac mortality, during a median follow-up of 41 months.Results: Day-time PB occurred in 145/380 patients who had more severe HF and more compromised left ventricular function (p