Infections complicating orthotopic liver transplantation: a study emphasizing graft-related septicemia.
Infections complicating orthotopic liver transplantation: a study emphasizing graft-related septicemia.
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原位肝移植并发感染：一项强调移植物相关败血症的研究。
DOI：
10.1001/archsurg.1976.01360300027004
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发表时间：
1976
影响因子：
--
通讯作者：
T. Starzl
中科院分区：
文献类型：
--
作者：
G. Schröter;M. Hoelscher;C. Putnam;K. Porter;J. Hansbrough;T. Starzl
102例同种异位同种肝移植的93名受者中，菌血症或真菌血症的发生率超过70%。移植物本身通常是免疫性和非免疫性实质损伤后全身感染的入口部位，特别是在胆道引流缺陷的情况下。同种移植物本身作为特殊感染危险因素的作用促使更多地使用去功能化空肠 Roux 肢体来减少移植物污染。它还刺激了非常积极的术后诊断工作，以排除移植的补救性机械并发症。
In 93 recipients of 102 orthotopic liver homografts, the incidence of bacteremia or fungemia exceeded 70%. The graft itself was usually an entry site for systemic infection after both immunologic and nonimmunologic parenchymal injury, especially if there was defective biliary drainage. The role of the homograft itself as the special infectious risk factor has prompted increased use of defunctionalized jejunal Roux limbs to reduce graft contamination. It has also stimulated very aggressive postoperative diagnostic efforts to rule out remedial mechanical complications of the transplant.