The Effect of Bladder Filling Rate on the Voiding Behavior of Patients with Overactive Bladder
The Effect of Bladder Filling Rate on the Voiding Behavior of Patients with Overactive Bladder
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DOI：
10.1097/ju.0000000000000199
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发表时间：
2019-08-01
影响因子：
6.6
通讯作者：
Flood, Hugh D.
中科院分区：
文献类型：
--
作者：
Redmond, Elaine J.;O'Kelly, Therese;Flood, Hugh D.
目的：许多自助指南建议患者，在一天中分散液体摄入量可以减少膀胱过度活动症的症状。然而，尽管动物研究表明更快的充盈速率和传入神经放电增加之间存在联系，但据我们所知，充盈速率和膀胱感觉之间的关系尚未在人类中进行过研究。本研究旨在探讨膀胱容量和膀胱充盈率对膀胱过度活动症患者膀胱感觉和排尿方式的影响。从泌尿科门诊招募了另外24名膀胱过度活动症女性患者。每个参与者完成UDI-6（尿窘迫量表，简表），IIQ-7（排尿影响问卷，简表）和3天感觉相关膀胱日记。结果：对照组中紧急排尿的比例随着排尿量和膀胱充盈率的增加而增加（每个P <0.05）。
Purpose: Many self-help guides advise patients that spreading fluid intake throughout the day can reduce overactive bladder symptoms. However, although animal studies suggest a link between a faster filling rate and increased afferent nerve firing, to our knowledge the relationship between the filling rate and bladder sensation has not been examined in humans. The aim of this study was to investigate the effect of bladder volume and the bladder filling rate on the bladder sensation and voiding patterns of patients with overactive bladder.Materials and Methods: A control group of 40 female volunteers were recruited by open advertisement. A further 24 female patients with overactive bladder were recruited from the urology outpatient department. Each participant completed the UDI-6 (Urinary Distress Inventory, Short Form), the IIQ-7 (Incontinence Impact Questionnaire, Short Form) and a 3-day sensation related bladder diary.Results: The proportion of urgent voids in the control group increased with increasing voided volume and bladder filling rates (each p