Polymorphous low-grade adenocarcinoma with cavernous sinus involvement presenting as third nerve palsy.
Polymorphous low-grade adenocarcinoma with cavernous sinus involvement presenting as third nerve palsy.
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DOI：
10.1016/j.ajoc.2022.101460
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发表时间：
2022-06
影响因子：
--
通讯作者：
Welsbie DS
中科院分区：
文献类型：
--
作者：
Chan AX;Chang A;Do JL;Koo SJ;Lin G;Welsbie DS
多形性低度腺癌是一种唾液腺肿瘤，通常位于口腔内。我们提出了一个孤立性第三脑神经麻痹的病例，这是青光眼手术后患者状态中累及左侧海绵窦的多形性低级别腺癌的初始表现。一名 68 岁女性左眼植入青光眼引流装置后，术后十周出现孤立性左第三神经麻痹。鉴别诊断包括微血管缺血性神经病、术后上睑下垂和压迫性肿块。 MRI 显示左侧海绵窦肿块，随后的切除活检显示多形性低级别腺癌的诊断。很少有病例报告起源于鼻咽并延伸到鼻咽以外的多形性低级别腺癌。本报告强调了这种唾液腺肿瘤的意想不到的神经眼科表现。
Polymorphous low-grade adenocarcinoma is a tumor of the salivary glands that typically localizes within the oral cavity. We present a case of isolated third cranial nerve palsy as the initial presentation of polymorphous low-grade adenocarcinoma involving the left cavernous sinus in a patient status post glaucoma surgery. A 68-year-old woman status post glaucoma drainage device implantation in her left eye presented with an isolated left third nerve palsy ten weeks postoperatively. Differential diagnoses included microvascular ischemic neuropathy, postoperative ptosis, and compressive mass. MRI revealed a left cavernous sinus mass, and subsequent excisional biopsy revealed a diagnosis of polymorphous low-grade adenocarcinoma. There are few cases reporting polymorphous low-grade adenocarcinoma originating from and extending beyond the nasopharynx. This report emphasizes an unexpected neuro-ophthalmic manifestation of this salivary gland tumor.