Diffusion-Weighted Imaging Shows a False-Negative Finding for Bone Marrow Involvement on 18F-FDG PET/MRI in a Patient With Malignant Lymphoma After Blood Transfusion
Diffusion-Weighted Imaging Shows a False-Negative Finding for Bone Marrow Involvement on 18F-FDG PET/MRI in a Patient With Malignant Lymphoma After Blood Transfusion
复制标题
弥散加权成像显示恶性淋巴瘤患者输血后 18F-FDG PET/MRI 出现骨髓受累的假阴性结果
DOI：
10.1097/rlu.0000000000002052
复制
发表时间：
2018
影响因子：
10.6
通讯作者：
Murakami Takamichi
中科院分区：
文献类型：
--
作者：
Zeng Feibi;Nogami Munenobu;Shirai Taiichiro;Zen Yoh;Murakami Takamichi
铁超载是输血过程中的主要并发症。本报告提出一个恶性淋巴瘤的病例，其中骨髓受累的结果是不一致的18氟脱氧葡萄糖PET成像研究和磁共振成像与扩散加权成像研究。在这种情况下，PET成像研究为恶性淋巴瘤阳性，而MRI研究为阴性。由于输血后铁过载导致网状内皮系统中的铁沉积被认为是弥散加权成像信号强度降低的原因，导致MRI假阴性结果。
Iron overload is a major complication in blood transfusion procedures. This report presents a case of malignant lymphoma, in which the findings of bone marrow involvement were discordant between 18 F-FDG PET imaging studies and MRI with diffusion-weighted imaging studies. In this case, the PET imaging studies were positive for malignant lymphoma, whereas the MRI studies were negative. Iron deposition in the reticuloendothelial system due to posttransfusion iron overload was considered to be the cause of the decrease in signal intensity on diffusion-weighted imaging, resulting in a false-negative finding on MRI.