Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men
Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men
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DOI：
10.1677/joe.0.1760163
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发表时间：
2003-01-01
影响因子：
4
通讯作者：
Góñez, C
中科院分区：
文献类型：
--
作者：
Gonzales, GF;Córdova, A;Góñez, C
麻黄是一种秘鲁下胚轴，仅生长在安第斯山脉中部4000至4500米之间。玛卡在安第斯地区传统上是因为它的催情和/或促进生育的特性而被使用。这项研究是一项为期12周的双盲、安慰剂对照、随机、平行试验，其中不同剂量的玛卡Gelatinizada的积极治疗与安慰剂进行了比较。这项研究旨在验证这样一种假设，即玛卡在服用壮阳药和/或提高生育能力的剂量时，对表面上健康的男性的血清生殖激素水平没有影响。在服用安慰剂或Maca(1.5g或3.0g/d)前、治疗2周、4周、8周和12周时，分别检测血清黄体生成素、卵泡刺激素、催乳素、17-α-羟孕酮、睾酮和17-β雌二醇水平。数据显示，与安慰剂相比，玛卡对所研究的任何荷尔蒙都没有影响，荷尔蒙也没有随着时间的推移显示出任何变化。多元回归分析显示，在研究的任一时间点，玛咖治疗对血清睾酮水平均无显著影响(P>0.05)。结论：玛咖治疗不影响血清生殖激素水平。
Lepidium meyenii (Maca) is a Peruvian hypocotyl that grows exclusively between 4000 and 4500 m in the central Andes. Maca is traditionally employed in the Andean region for its supposed aphrodisiac and/or fertility-enhancing properties.This study was a 12-week double-blind, placebo-controlled, randomized, parallel trial in which active treatment with different doses of Maca Gelatinizada was compared with a placebo. The study aimed to test the hypothesis that Maca has no effect on serum reproductive hormone levels in apparently healthy men when administered in doses used for aphrodisiac and/or fertility-enhancing properties. Men aged between 21 and 56 years received 1500 mg or 3000 mg Maca.Serum levels of luteinizing hormone, follicle-stimulating hormone, prolactin, 17-alpha hydroxyprogesterone, testosterone and 17-beta estradiol were measured before and at 2, 4, 8 and 12 weeks of treatment with placebo or Maca (1.5 g or 3.0 g per day). Data showed that compared with placebo Maca had no effect on any of the hormones studied nor did the hormones show any changes over time. Multiple regression analysis showed that serum testosterone levels were not affected by treatment with Maca at any of the times studied (P, not significant).In conclusion, treatment with Maca does not affect serum reproductive hormone levels.