Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy
Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy
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DOI：
10.1002/hed.20221
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发表时间：
2005-08-01
影响因子：
2.9
通讯作者：
Camilo, ME
中科院分区：
文献类型：
--
作者：
Ravasco, P;Monteiro-Grillo, I;Camilo, ME
背景我们的目的是确定饮食咨询或口服补充剂对癌症患者放疗期间和放疗后3个月的结果的影响，特别是营养结果、发病率和生活质量（OOL）。将75例接受放疗（RT）的头颈癌患者随机分为以下组：第1组（n = 25），接受常规食物饮食咨询的患者;第2组（n = 25），维持常规饮食加补充剂的患者;第3组（n = 25），维持随意摄入的患者。在基线、FIT结束时和3个月时评估营养摄入（通过饮食史确定）和状态（通过Ottery的主观总体评估确定）以及QOL（通过欧洲癌症研究和治疗组织生活质量问卷3.0版[EORTC QLQ-C30]确定）。RT后第1组和第2组的能量摄入增加（p
Background. We aimed to determine the effect of dietary counseling or oral supplements on outcome for patients with cancer, specifically, nutritional outcome, morbidity, and quality of life (OOL), during and 3 months after radiotherapy.Methods. Seventy-five patients with head and neck cancer who were referred for radiotherapy (RT) were randomized to the following groups: group 1 (n = 25), patients who received dietary counseling with regular foods; group 2 (n = 25), patients who maintained usual diet plus supplements; and group 3 (n = 25), patients who maintained intake ad lib. Nutritional intake (determine by diet history) and status (determined by Ottery's Subjective Global Assessment), and QOL (determined by the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire version 3.0 [EORTC QLQ-C30]) were evaluated at baseline, at the end of FIT and at 3 months.Results. Energy intake after RT increased in both groups 1 and 2 (p